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Doses were escalated every 4 weeks until the target dose was reached, following the FDA- and EMA-approved labels [10, 11]

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Research has examined MT-1's effects on multiple research areas, including melanocortin receptor binding and selectivity, second-messenger pathway activation (cAMP/PKA signaling), pigmentation-related gene expression, neuroinflammation-linked signaling, cardiovascular pathway modulation, and metabolic endpoint evaluation in controlled in-vitro and preclinical animal models